10 CALCIUM GLUCONATE ANTIDOTE SKIN
10 CALCIUM GLUCONATE ANTIDOTE PLUS

Discuss with Poisons Information Centre 131126 regarding subcutaneous infiltration of Calcium gluconate 0.5 mL/cm2, regional IV infusion or intra-arterial infusion.Nebulised 1 mL Calcium gluconate 10 % in 3 mL 0.9 % sodium chloride.Calcium gluconate 2.5 % gel topically and repeated 15 minutely.Correct hypocalcaemia and other electrolyte abnormalities.May require repeated and higher doses.For deficiency 0.2 mL/kg (= 0.4 mmol/kg) over 4 hours.For ventricular fibrillation 0.05 - 0.1 mL/kg (= 0.1 - 0.2 mmol/kg) slow IV.

10 CALCIUM GLUCONATE ANTIDOTE PLUS

Plus IV Magnesium sulfate 50 %, 2 mmol/mL:.

Plus IV Sodium bicarbonate8.4 % (1 mmol/ml).

0.5 mL/kg up to 60 mL (note: this dose is higher than standard maximum dose).

If cardiac arrest or ventricular arrhythmias:.

All patients at risk of fluorosis need to be managed in a resuscitation area and have continuous cardiac monitoring.

Ingestion - activated charcoal is not indicated.

Ensure that staff do not become contaminated - wear PPE, including chemical resistant gloves.

Wash off, including scrubbing under nails.

Remove clothing and jewellery, bag in sealed containers and remove from patient care areas to protect other patients and health care workers from exposure.

If not available, an extemporaneous gel can be prepared by adding 10 mL of calcium gluconate injection 10% to 30 mL of sterile surgical lubricant.

Repeat 15 minutely until pain has stopped.

Apply Calcium gluconate 2.5 % gel to contaminated skin.

Consider referral for urgent endoscopy in cases of ingestion.

ECG - prolonged QT is a marker of hypocalcaemia.

Electrolytes and blood gas - hypocalcaemia, hypomagnesaemia, hypo/hyperkalaemia,.

immediate irritation but cough, wheeze and SOB may be delayed.Īlways check for Medicalert bracelet in any unconscious patient, or any other signs of underlying medical condition (fingerprick marks etc) Investigations.

Oesophageal irritation occurs with concentrations <20%.

10 CALCIUM GLUCONATE ANTIDOTE SKIN

Assessment of burns due to skin exposure (see burns CPG).May be disproportionate to other clinical signs.

Pain as marker of tissue destruction may be experienced before any external signs of blistering or skin erythema.Immediate with concentrations > 50% but will be delayed for up to 24 hours with weaker solutions.Perioral numbness, paraesthesias, muscle cramps.Symptoms of resultant hypocalcaemia and hypomagnesaemia, including:.Determine method of exposure (topical, ingested and inhaled), BSA exposed.Determine if intentional exposure or accidental.any ingestion as risk of systemic fluorosis.Greater than 5% BSA with any concentration.It is available in concentrations up to 70%, though in domestic applications is likelyġ% body surface area (BSA) with > 50% concentration HF.HF is found in rust cleaners, car wheel cleaners (aluminium brightener) and is used in glass etching, as well as for industrial applications.HF is corrosive, and systemically toxic by any route, due to fluorosis which manifests as hypocalcaemia.Local anaesthetic techniques are not appropriate for pain relief as they may mask ongoing symptoms.įor 24 hour advice, contact Victorian Poisons Information Centre 131126 Background.Pain may be delayed and disproportionate to external signs.Topical exposure to Hydrofluoric Acid (HF) can cause systemic hypocalcaemia.Poisoning – Acute Guidelines for Initial Managementīurns / management of burn wounds Key points

10 calcium gluconate antidote